Nimblegen Service

NimbleGen microarrays are oligonucleotide microarrays synthesized in situ by maskless array synthesizer (MAS) technology, which is a synthesis of digital projection technology and combinatorial chemistry. At the heart of MAS is the digital micromirror device (DMD), which contains about 786,000 tiny aluminium mirrors on a computer chip, each of which is individually addressable and freely programmable. UV light is projected onto the DMD and - dependent on micromirror position - passes to a defined spot of oligonucleotide synthesis on the array surface. UV light exposure results in decoupling of protection groups, making the oligonucleotide available for the next coupling step. MAS technology is extremely flexible and allows a rapid change of array design. New arrays can be produced within a few hours.
Service for Geneexpression, ChIP-chip, CGH and GGR available.