Solution for Drug Development

Beckman Coulter introduced the Biomek FX AdmetOx Workstation for in vitro drug permeability measurements. This new, validated solution automates the PAMPA (Parallel Artificial Membrane Permeability Analysis) method for the determination of passive absorption of a drug candidate through an artificial lipid membrane. Made possible through an agreement between the companies, the high-throughput system automates PIons's method for PAMPA analysis on Beckman Coulter's Biomek FX liquid handling system. The method provides significant time savings as compared to the Caco-2 cell-based method, which takes over three weeks to complete.