Higher Loads for Pharmaceutical Lab-Scale Purification

Phenomenex ha introduced a 30 mm I.D. (internal diameter) Kinetex core-shell 5-micron column in Axia hardware for preparative HPLC and SFC in pharmaceutical lab-scale purification. Also offered in a 21.2 mm I.D., the 30 mm column enables increased sample loading and throughput.

With the addition of this larger diameter column, the company offers the only core-shell media line that can be used from analytical scale through scale-up to purification. The Axia preparative format delivers long column lifetime, high efficiencies, performance, and high reproducibility.

5-micron is the largest particle in the core-shell family and delivers better performance than 5-micron fully porous offerings, with no increase in backpressure. According to the company 5-micron media provides 60 to 90 percent higher average efficiencies compared to the same size fully porous columns with little to no method development.