09/16/2008 • Analytics • Focus on Products at Analytica

Oxyma Pure

Recent years have seen increasing transport limitations being imposed on common peptide coupling additives, such as hydroxybenzotriazole1 and its congeners. The urgent need for a safe racemization suppressing additive has now been addressed by Luxembourg Biotechnologies Ltd..
Indeed, Luxembourg Biotechnologies Ltd., together with Professors Fernando Albericio2 and Ayman El-Faham3 have undertaken major research efforts aimed at improving peptide coupling technologies. As part of this work, Oxyma Pure, one of the most effective coupling additives known was found to be a very promising racemization suppressant.

It has recently been shown4 that Oxyma Pure is probably the most effective racemization suppressing coupling additive known to date.
This kinetics-enhancing compound is more economical than HOAt the leading analogue of the hydroxybenzotriazole additives, it is not explosion-prone or allergenic.
An added advantage of its use is that with Oxyma Pure, the coupling progress can be visually monitored by color change.

Furthermore, since the Oxyma Pure is more safe than the above hydroxybenzotriazole compounds, Oxyma Pure can be safely transported by air or by sea without the need of deactivating additives.

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Livchem GmbH & Co. KG

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65933 Frankfurt

Phone: +49 (0) 69 3800 2685
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