05/13/2008 • Analytics • Laboratory appliances

Biotherapeutics Analysis Solution

Bruker Daltonics introduced its Maldi-TDS TOF/TOF based tools for biologics drug development and quality control in the pharmaceutical and biotechnology industries. It is available on the companys Ultraflex III TOF/TOF system for the characterisation of recombinant proteins with regard to sequence, C- and N-terminal assignments, Pegylation sites and other modifications. Recently, the Maldi-TDS approach has been used to characterise two batches of recombinant proteins provided by the ABRF Protein Research Group (PRG) with the ultraflex IIIs reISD (reflector in-source decay) Maldi top-down sequencing capability for unmatched 100% sequence coverage for all of the three different truncation variants to be determined. The top-down analysis on the ultraflex III system comprised simultaneously the assignment of all the N/C-termini of the recombinant proteins.

This product information
is expired!

Use our search-function for current products ...
gradient arrows

Bruker Daltonik GmbH

Fahrenheitstr. 4
28359 Bremen

Phone: 049/421 2205-0
Fax: 049/421 2205-103