05/02/2007 • Focus on Products at Analytica • Laboratory appliances

bio-t® bag – the disposable Bioreactor System

The disposable bioreactor system from zeta allows you to step into the disposable age. The popular single-use cultivation system represents a successful collaboration between Meissner and zeta. The DPSTM bag technology from Meissner and zeta’s classical fermentor knowledge from bio-t® mini and bio-t® pro combined with the innovative agitation system makes the disposable bioreactor system from zeta a powerful tool for the upcoming future trend.

Bioreactor System:
  • Presterilized, disposable bio-t® bag with integrated single-use measuring probes and mixing element allowing a gasket free agitation
  • Open, double jacket stainless steel supporting container to take up disposable bag for heating and cooling
  • Vibro mixer with frequency and amplitude for free configuration
  • Bioreactor platform to hold vibro mixer and supporting container into position
  • Bag hanger to take up all supply bags for acid, base and nutrient addition or sampling.
Control System:
Hardware:
  • Compact and easy to clean stainless steel housing
  • Control system with 8“ color touch screen
  • Heating circuit
  • Controller for temperature, agitation (frequency and amplitude), pH and pO2
  • 4 free to configure peristaltic pumps and rotameter
  • Connections for external pumps, pressure sensor and balance
  • Gas mixing station
Software Evolution® mini:
  • Simple menu-driven data entry
  • Measurement of various process parameters
  • Trend visualization and alarming
  • Manual or automatic control mode
  • Calibration menu
  • Password protected access levels
  • Time depended set point profile (Ramp function)
  • Cascade control for aeration (gas mix/agitation/feed)
SCADA:
  • Visualization and trending of process data on external PC
  • Data export to Excel
Predefined packages of the bio-t® bag disposable bioreactor system are available for bacterial culture and cell culture. In addition the gas mixing station can be realized in three different versions: Standard, Pulse Flow Control and Continuous Flow Control. The complete disposable bioreactor line is available in for up-scale within 3L, 15L, 75L, 375L and 1875L total volume.

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Zeta Biopharma GmbH

Zetaplatz 1
8501 Lieboch

Phone: +43/(0)3136/9010/0
Fax: +43/(0)3136/9010 /9100