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PLT VASP/P2Y12 Test for Monitoring of Thienopyridine / Clopidogrel Resistence

American Diagnostica offers test kits and reagents related to the diagnosis and research of disorders involving coagulation, fibrinolysis, and vascular biology.

PLT VASP/P2Y12 is a rapid (< 30 min) and simple flow cytometric assay to evaluate P2Y12 receptor antagonist drug effect through the measurement of the VASP phosphorylation state, an intracellular platelet protein.

An increasing number of publications describe patient cases affected by clopidogrel resistance. The thienopyridine drug family irreversibly inhibit P2Y12 receptor. Thienopyridine resistance can be easily assessed with the PLT VASP/P2Y12 assay.

PLT VASP/P2Y12 features :

1. 48-hour sample stability before testing (at room temperature)  => very convenient for clinical studies and sample shipping
   
   
2. only 30 µL of whole blood requested. Even if this is a dual color analysis, no fluorescence compensation is needed.